|
|
17alpha,21-dihydroxy-5beta-pregnane-3,11,20-trione + NADP+ <=> H+ + cortisone + NADPH
|
1.3.1.3
Delta4-3-oxosteroid 5beta-reductase
|
–
|
K
|
| |
BRENDA:
BR36811
KEGG:
R02893
MetaCyc:
CORTISONE-BETA-REDUCTASE-RXN
SABIO-RK:
2753
|
|
|
|
17alpha,21-dihydroxy-5alpha-pregnan-3,11,20-trione + NADP+ <=> cortisone + NADPH + H+
|
1.3.1.22
3-oxo-5alpha-steroid 4-dehydrogenase (NADP+)
|
–
|
|
| |
BRENDA:
BS258530
KEGG:
R02892
MetaCyc:
CORTISONE-ALPHA-REDUCTASE-RXN
|
|
|
|
cortisol + NADP+ <=> cortisone + NADPH + H+
|
1.1.1
1.1.1.146
11beta-hydroxysteroid dehydrogenase
1.1.1.B40
|
–
–
–
|
K
|
| |
BRENDA:
BS370906
KEGG:
R02836
MetaCyc:
RXN-12085
SABIO-RK:
2701
|
|
|
|
cortisol + NAD+ <=> cortisone + NADH
|
1.1.1
1.1.1.146
11beta-hydroxysteroid dehydrogenase
1.1.1.51
3(or 17)beta-hydroxysteroid dehydrogenase
1.1.1.B40
|
–
–
–
–
|
K
|
| |
BRENDA:
BS370905
KEGG:
R02834
SABIO-RK:
2700
|
|
|
|
cortisone + reduced_adrenodoxin + O2 <=> 15beta-hydroxycortisone + oxidized_ferredoxin + H2O
|
1.14.15.8
steroid 15beta-monooxygenase
|
–
|
|
| |
BRENDA:
BS443403
|
|
|
|
cortisol + reduced_ferredoxin + O2 <=> cortisone + oxidized_ferredoxin + H2O
|
1.14.15.4
steroid 11beta-monooxygenase
|
–
|
|
| |
BRENDA:
BS186785
|
|
|
|
cortisone + NADH <=> 17alpha,20beta,21-Trihydroxy-pregn-4-ene-3,11-dione + NAD+
|
1.1.1.53
3alpha(or 20beta)-hydroxysteroid dehydrogenase
|
–
|
|
| |
BRENDA:
BS188330-a
|
|
|
|
cortisone + NADPH + H+ <=> 20beta-hydroxycortisone + NADP+
|
1.1.1.53
3alpha(or 20beta)-hydroxysteroid dehydrogenase
|
–
|
|
| |
BRENDA:
BS426141
|
|
|
|
cortisone + NADPH <=> cortisole + NADP+
|
1.1.1.146
11beta-hydroxysteroid dehydrogenase
|
–
|
|
| |
BRENDA:
BS370907
|
|
|
|
cortisone + NADPH <=> 11beta,21dihydroxy-pregnan-3,11,20-trione + NADP+
|
1.3.1.3
Delta4-3-oxosteroid 5beta-reductase
|
–
|
|
| |
BRENDA:
BS258418
|
|
|
|
cortisone + NADPH <=> 17alpha,20beta,21-Trihydroxy-pregn-4-ene-3,11-dione + NADP+
|
1.1.1.53
3alpha(or 20beta)-hydroxysteroid dehydrogenase
|
–
|
|
| |
BRENDA:
BS188330
|
|
|
|
11-Dehydrocorticosterone + NADPH + H+ <=> cortisone + NADP+
|
1.1.1.146
11beta-hydroxysteroid dehydrogenase
|
–
|
|
| |
BRENDA:
BS438657
|
|
|
|
17alpha-hydroxy-pregn-4-ene-3,11,20,21-tetraone + NADPH <=> cortisone + NADP+
|
1.1.1.151
21-hydroxysteroid dehydrogenase (NADP+)
|
–
|
|
| |
BRENDA:
BS187303
|
|
|
|
3''-phosphoadenylylsulfate + cortisone <=> adenosine_3'',5''-bisphosphate + Cortisone_21-sulfate
|
2.8.2.2
alcohol sulfotransferase
|
–
|
|
| |
BRENDA:
BS360321
|
|
|
|
Cortisone_21-sulfate + H2O <=> cortisone + sulfate
|
3.1.6.2
steryl-sulfatase
|
–
|
|
| |
BRENDA:
BS93860
|
|
|
|
cortisone + acceptor <=> Prednisone + reduced_acceptor
|
1.3.99.4
3-oxosteroid 1-dehydrogenase
|
–
|
|
| |
BRENDA:
BS258854
|
|
|
|
H+ + NADPH + cortisone <=> NADP+ + 11beta,17alpha,20alpha,21-Tetrahydroxy-4-pregnene-3-one
|
1.1.1.149
20alpha-hydroxysteroid dehydrogenase
|
–
|
|
| |
SABIO-RK:
10639
|
|
|
|
NADH + 21-dehydrocortisone + H+ <=> NAD+ + cortisone
|
1.1.1.150
21-hydroxysteroid dehydrogenase (NAD+)
|
–
|
|
| |
SABIO-RK:
11536
|
|
|
|
21-dehydrocortisone + H+ + NADPH <=> NADP+ + cortisone
|
1.1.1.151
21-hydroxysteroid dehydrogenase (NADP+)
|
–
|
|
| |
SABIO-RK:
11542
|
|
